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SANIpore® DS

SANIpore® Ds PES (Polyethersulfone) Membranes

SANIpore® Ds filter cartridges feature advanced double-layer polyethersulfone (PES) membranes, designed for superior sterile filtration. These filters offer excellent microbial retention and cost-effective performance, making them ideal for sterilization and clarification of pharmaceutical and biological solutions.

The SANIpore® Ds PES filters can be sterilized repeatedly using steam or hot water, which extends their service life and reduces replacement costs. With polyethersulfone’s low protein binding and broad chemical compatibility, these filters are perfect for processing valuable biological products, including vaccines and protein solutions. SANIpore® Ds membrane filters are fully validated as sterilizing-grade filters, meeting international standards for regulatory compliance.

SANIpore® DS
  • Features and Quality

    • Double-layer membrane structure provides excellent relibility and safety
    • Large effective filtration area (0 58 m2/10 inch)
    • Can be steam sterilized up to 50 sterilization cycles
    • Complies with Food Contact Regulations: FDA 21CFR177-182 and 1935/2004 EC
  • Key Applications of SANIpore® DS PES Membranes

    • Vaccine Filtration
    • Cell and Tissue Culture Media Processing
    • Large Volume Parenteral (LVP) Solutions
    • Water for Injection (WFI) Systems
    • Diagnostic Reagents and Solutions
    • Ophthalmic Formulations
    • Protein and Biologics Filtration
    • Serum and Blood Product Clarification
Features and Quality

Construction of Materials

Filter Membrane Double-Layer PES Membrane
Media Support Polypropylene
End Caps Polypropylene
Inner Core Polypropylene
Outer Cage Polypropylene
Sealing Method Thermal Bonding
O-rings Buna, Viton (or FKM), EP, Silicone, Encapsulated   Silicone, Encapsulated Viton (or FKM)

Maximum Operating Parameters

Differential Pressure ●Forward 50 psid (3.4 bard)at 20 C(68 °F)

●Reverse 40 psid (2.7 bard) at 20 C(68 °F)

Operating Temperature 82°C(180 °F) at 10 psid (0.69 bard) in water
Recommended Changeout Pressure 35psid (2 .4bard)

Cartridge Integrity Test Specifications

Pore size Minimum Bubble point
0.1um 32PSI/2.2barg (IPA)
0.2um 55.1PSI/3.8barg(water)
0.45um 39.2/2.7barg(water)

Water Flow Characteristic

Water Flow Characteristic

612 51 0010 30 01 S A P
Filter Type
612=SANIpore® DS
Fliter Configuration
51=Cartridge
Pore Size
0010=0.1um
0020=0.22um
0045=0.45um
Filter Size
30=5″
31=10″
33=20″
34=30″
35=40″
Connector
01=222Fin
02=222Flat
03=226Fin
04=226Flat
05=DOE
O-Ring
S=Silicone
E=EPDM
V=Viton
Sterilization
A=Autoclave
P=Pharmaceutical grade

Features and Quality

Features and Quality

Features and Quality

  • Double-layer membrane structure provides excellent relibility and safety
  • Large effective filtration area (0 58 m2/10 inch)
  • Can be steam sterilized up to 50 sterilization cycles
  • Complies with Food Contact Regulations: FDA 21CFR177-182 and 1935/2004 EC

Specification and Data

Construction of Materials

Filter Membrane Double-Layer PES Membrane
Media Support Polypropylene
End Caps Polypropylene
Inner Core Polypropylene
Outer Cage Polypropylene
Sealing Method Thermal Bonding
O-rings Buna, Viton (or FKM), EP, Silicone, Encapsulated   Silicone, Encapsulated Viton (or FKM)

Maximum Operating Parameters

Differential Pressure ●Forward 50 psid (3.4 bard)at 20 C(68 °F)

●Reverse 40 psid (2.7 bard) at 20 C(68 °F)

Operating Temperature 82°C(180 °F) at 10 psid (0.69 bard) in water
Recommended Changeout Pressure 35psid (2 .4bard)

Cartridge Integrity Test Specifications

Pore size Minimum Bubble point
0.1um 32PSI/2.2barg (IPA)
0.2um 55.1PSI/3.8barg(water)
0.45um 39.2/2.7barg(water)

Water Flow Characteristic

Water Flow Characteristic

Ordering Information

612 51 0010 30 01 S A P
Filter Type
612=SANIpore® DS
Fliter Configuration
51=Cartridge
Pore Size
0010=0.1um
0020=0.22um
0045=0.45um
Filter Size
30=5″
31=10″
33=20″
34=30″
35=40″
Connector
01=222Fin
02=222Flat
03=226Fin
04=226Flat
05=DOE
O-Ring
S=Silicone
E=EPDM
V=Viton
Sterilization
A=Autoclave
P=Pharmaceutical grade

Common questions about Sanitek

Common Questions about SanitekWhat is the asymmetric PES?

The size of the apertures changes along the membrane’s thickness, with the greatest openings appearing on one side and the smallest openings on the other. Each side of the membrane appears slightly different when viewed with reflected light at low incidence angles. In comparison to the side with the smallest pores, the side with the greatest pores will appear more matte or dull (which will appear shinier).

The majority of people can quickly distinguish the sides if they have some experience. Without effecting retention, the membranes can be utilized with either surface pointed upstream. However, pointing the bright side upstream enables more accurate examinations of the retained particles while orienting the dull side upstream boosts overall throughput.

Common Questions about SanitekHow do you assure the quality of your products?

At Sanitek, we pay attention to the details of every link and strictly adhere to ISO 9001:2008 and ISO 13485:2005 standards to ensure the quality of our products.

In the raw material procurement phase, we work with reliable suppliers to ensure that the quality of raw materials meets our standard requirements.

In the production process, we strictly control the quality of each link to ensure that the manufacturing process of the product is stable and reliable. At the factory inspection stage of the final product, we carry out a comprehensive quality check to ensure that the product meets the customer’s requirements and specifications.

Common Questions about SanitekWhat support can I expect from Sanitek in case of issues?

In case of any issues, Sanitek will respond promptly to assist you in analyzing the problem and finding out the cause. We retain the raw material of all shipments, which is essential for identifying if the issue originates from the membrane. While incidents are extremely rare, if the problem is confirmed to be from the membrane, we will take corrective action, including prioritized full replacement of the affected lot.

Common Questions about SanitekWhat is the difference between hydrophilic and hydrophobic membrane filters?

Hydrophilic membranes readily absorb water due to surface tension, allowing water to flow through their pores. These filters are commonly used for water and aqueous solutions but are unsuitable for air or gas filtration, as they would block flow if wetted.

Hydrophobic membranes, on the other hand, repel water, preventing it from entering the pores unless pressure exceeds a certain threshold. These filters are typically used for air, gas, or non-aqueous fluid filtration. When used with water, hydrophobic filters must first be pre-wetted with a compatible fluid to allow water flow.

Common Questions about SanitekWhat are the advantages of PES membrane filters?

PES membrane filters offer low protein binding, making them an excellent choice for applications like tissue culture media sterilization, as well as in life sciences and microbiology. Their unique properties ensure minimal interference with sensitive fluids, maintaining the integrity of the solution.

Common Questions about SanitekWhat is the difference between nominal and absolute pore size ratings?

Nominal pore size ratings offer a general indication of filter retention but may allow particles equal to or slightly larger than the rated size to pass through. These ratings can vary between manufacturers and may not always represent identical retention capabilities.

Absolute pore size ratings, on the other hand, are determined through retention tests using known microorganisms or particles, indicating the smallest size fully retained by the filter. These ratings are more consistent across manufacturers and are often tied to bubble point specifications. However, application conditions can still affect particle retention, even for filters with absolute ratings.

Common Questions about SanitekCan polyethersulfone (PES) membrane filters be used for lateral flow applications?

PES membrane filters are generally not suitable for lateral flow assays due to their low protein binding capacity. Lateral flow applications typically require membranes that can bind proteins more effectively.

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